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Using Time in Range (TiR) and HbA1c together to help manage your diabetes

Find out how you can use both these blood sugar measurements together to get a better understanding of your diabetes.

Together with HbA1c, Time in Range can help you and your healthcare professional to get a more complete picture of your blood sugar over time and this may help to reduce your risk of health complications.1,2,3

HbA1c gives your average blood sugar over three months and Time in Range adds to this by giving you results over 24-hour periods.1

HbA1c is a traditional and useful measure of blood sugar control but there are some things it cannot show, such as the daily fluctuations in your blood sugar levels that can be responsible for low blood sugar (hypoglycaemia) or high blood sugar (hyperglycaemia). For people who use a continuous glucose monitor (CGM), the peaks, dips and daily fluctuations in blood sugar can be seen.1

Read on to find out how Time in Range can work together with HbA1c by providing a more complete picture of your blood sugar control.1

This quick-reference guide shows you how to read TiR from a special report on your CGM

A three-month average versus a 24-hour picture

HbA1c is a useful measure that shows your average blood sugar levels for the previous three months.1 In other words, it gives you a historical average of your blood sugar levels over a three-month period. HbA1c is generally seen as the ‘gold standard’ in diabetes management and has been used for a long time.4 It is the best-known and best-studied measurement, but some scientists are starting to think that Time in Range could be a better indicator of your risk of diabetes complications over time.1,2,5

Unlike with CGM use, HbA1c cannot show you the 24-hour fluctuations in your blood sugar or any peaks and dips.1 In fact, people with the same HbA1c results could have very different blood sugar patterns.4,6

Here is an example:

Two people with the same HbA1c can have different blood sugar patterns. 

Both Peter and Christina appear to have good diabetes blood sugar control, as their Hb1Ac test results were both 7%, but a closer look shows a different picture.6 This extra information is vital to help make those small but important lifestyle and behavioural changes needed to live well with diabetes.1

Diagrams are for illustrative purposes only

Short animation of the differences between Time in Range and HbA1c

Time in Range gives a more complete picture of your blood sugar control; a personalised view that shows how long you spend in your target blood sugar range (between 70 and 180 mg/dl or 3.9–10 mmol/l, for most people).1  Experts recommend that if you have type 1 or type 2 diabetes, most people should try to spend at least 17 hours (70%) of their day within this range.1 Different people may have slightly different targets for both HbA1c and TiR.1,2  Talk to your doctor to understand what your target range is.

Time in Range and HbA1c work together to give a more complete picture of your health

We now know that it is not just periods of high blood sugar levels (hyperglycaemia) that increase the risk of diabetes-related health problems, but also when blood sugar levels fluctuate. The more time you spend above and below range, the greater your risk of complications such as damage to your eyes and kidneys, or even cardiovascular disease.2,3

HbA1c can be used to predict your risk of developing these health complications, and aiming for an HbA1c of below 7% can reduce this risk.2,3

The more time you spend in your target blood sugar range (TiR), the more likely you are to reduce your diabetes health risks.1,2,3

Time in Range means fewer finger pricks

HbA1c and TiR are measured differently. HbA1c is measured using a diabetes blood test which must to be sent to a laboratory. Time in Range is measured during your everyday life using the numbers from a continuous glucose monitoring device (CGM).1 A CGM checks your ’interstitial’ glucose levels without you having to prick your finger or take any blood, using a sensor attached to your body.2 Interstitial glucose sounds complicated, but all it means is that the monitor measures the sugar level in the fluid under your skin but does not measure your blood sugar directly.2 The recent dramatic advances in digital health for diabetes and ‘diabetes tech’ have proved that CGMs can be very successful in helping people with diabetes stay within their target healthy blood sugar range.7  

Time in Range and HbA1c are both useful tools

Time in Range is not replacing HbA1c, but it can provide extra information to help support you and your healthcare professional to manage your diabetes.1,2,4  Some people with diabetes find it helpful to understand how their treatment and lifestyle are affecting their blood sugar levels. This knowledge can help them stay motivated with their diabetes management.8

Both TiR and HbA1c are very helpful tools to support you and your diabetes care team to make informed decisions that work for you and your health now and in the future.

This free CGM Cheat Sheet gives you the basics about starting with a CGM and TiR


 

This is general disease awareness and should not be understood as medical advice. If you have any questions or concerns, you should contact your healthcare professional.

References
  1. Battelino T, Danne T, Bergenstal RM, et al. Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations from the International Consensus on Time in Range. Diabetes Care 2019;42(8):1593–1603.
  2. Danne T, Nimri R, Battelino T, et al. International Consensus on Use of Continuous Glucose Monitoring. Diabetes Care 2017;40(12):1631-1640.
  3. Lu J, Wang C, Shen Y, et al. Time in Range in Relation to All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care. 2021; 44(2):549-555. 
  4. Chehregosha H, Khamseh ME, Malek M, et al. A View Beyond HbA1c: Role of Continuous Glucose Monitoring. Diabetes Ther. 2019; 10(3):853-863.
  5. American Diabetes Association. Glycemic Targets: Standards of Medical Care in Diabetes 2022. Diabetes Care 2022; 44 (Suppl 1):S73-S84.
  6. Kovatchev B, Cobelli C. Glucose variability: Timing, Risk, Analysis, and Relationship to Hypoglycemia in Diabetes. Diabetes Care 2016; 39: 502–510.
  7. Peek N, Sujan M, Scott P. Digital health and care in pandemic times: impact of COVID- BMJ Health Care Inform 2020;27(1):e100166.  
  8. Novo Nordisk. Data on file: TIR Patient Qualitative Research Global Summary Report. Data collection 2021–2022. 

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